Appendix 1
to the AB registration certificate–from the year
Brief characteristics of the drug
- Name
Trifuzol 1% solution for oral use.
- Composition
100 ml of solution contains the active substance:
piperidinium 2-[5-(furan-2-yl)-4-phenyl-1,2,4-triazol-3-ylthio]acetate 1.0 g.
Excipients: methylparaben, pyrogen-free water.
- Pharmaceutical (medicinal) form
Solution for oral use.
- Pharmacological properties
ATC vet classification code: QL03AX Other immunostimulants.
The active substance of the drug belongs to triazole derivatives. The mechanism of action of the active substance consists in the activation of biochemical processes in tissue cells. The drug has antiviral, antioxidant, immunomodulatory, anti-inflammatory, hepatoprotective and detoxifying effects, normalizes metabolism, strengthens the specific immune response to the administration of vaccines, increases the body’s resistance to diseases of viral etiology.
The active substance is excreted from the body 24 hours after the last use and is not detected in blood serum.
- Clinical features
5.1 Species of animals
Chickens, broiler chickens, repair young laying hens, laying hens, piglets.
5.2 Indications for use
The drug is used in chickens, broiler chickens, repair young laying hens, laying hens and piglets to improve the general resistance of the body, activate the specific immune response to the administration of vaccines, reduce post-vaccination complications, ensure antiviral action, avoid morbidity and mortality during periods of stress, increase performance indicators, including the European coefficient.
5.3 Contraindications
Poultry meat is used for human food after 10 days, eggs after 2 days, pork meat after 28 days after the last use of the drug.
5.4 Side effect
There are no data.
5.5 Special precautions for use
It is necessary to dilute the drug with water before use.
5.6 Interaction with other means and other forms of interaction
Strengthens the specific immune response to the administration of vaccines.
5.7 Doses and methods of administration to animals of different ages
For poultry, to strengthen the specific immune response, the drug is added to drinking water for drinking for two days before and two days after vaccination at the rate of 1 liter of the drug per 1 ton of water for 1 day. Also, to increase indicators of economic efficiency, including the European coefficient, the drug is used during 1, 2, 3 and 7, 8, 9, as well as, if necessary, 17, 18 and 19 days at the rate of 1 liter of the drug per 1 ton of water mixing with other drugs.
Weaning piglets and in the rearing group are given the drug with water at the rate of 1 liter per 1000 liters of water for 5 days to avoid morbidity and death of piglets during periods of stress and to increase average daily body weight gains.
Also, the drug is used for 5 days in a row to treat viral diseases of piglets or chickens at the rate of 1-2 liters of the drug per 1 ton of water.
5.8 Overdose (symptoms, emergency measures, antidotes)
There are no data.
5.9 Special disclaimers
It is necessary to dilute the drug with water before use.
5.10 Withdrawal period (grace period)
Poultry meat is allowed to be eaten by humans 10 days, eggs 2 days after the last use of the drug.
Pig meat is allowed to be used 28 days after the last use of the drug.
Meat or eggs received by the specified deadline are disposed of or fed to non-productive animals, depending on the opinion of the veterinary medicine doctor.
5.11 Special precautions for individuals and service personnel
Follow the rules for working with veterinary drugs.
- Pharmaceutical features
6.1 Forms of incompatibility (main)
There are no data.
6.2 Expiration Date
2 years.
The aqueous solution of the drug must be used on the day of preparation.
6.3 Specialstorage procedures
Dry, cool, protected from light place at a temperature of 8° to 15°C.
6.4 Nature and composition of the primary packaging container
Polymer bottles with a volume of 100, 1000 and 5000 ml.
6.5 Special safety measures when handling unused drug or its residues
The unused drug or its residues are disposed of in accordance with current requirements.
- Name and location of the owner of the registration certificate
LLC “NVP Lugfarma”
St. Kurchatova, building 6, office 9, Luhansk, Luhansk region, 91031, Ukraine
- Name and location of the manufacturer
Kharkiv State Biological Factory
prov. Rustaveli, bldg. 4, Kharkiv, Kharkiv region, 61050, Ukraine
- Additional information